The influence of the Mediterranean diet on glucose metabolism

Introduction: Insulin resistance is the first stage of diabetes development. It has been defined as a dysmetabolic state in which biological response target tissues (particularly liver, muscle and adipose tissue) to circulating insulin impaired. This leads hyperinsulinemia, turn obesity type 2 (T2D). The basic ingredients Mediterranean diet, such fruit, vegetables, fish rich fat, extra virgin olive oil, tree nuts, red wine, have functional food model by natural content nutraceuticals polyphenols, terpenoids, flavonoids, alkaloids, sterols unsaturated fatty acids. Purpose work : Demonstrate beneficial effects implementing diet patients with or diabetes. appropriate samples were accessed using search engine PubMed database. reviews meta-analyzes published over last 10 years used. Results: After changing these nutrients, greater improvement IR was shown obese people compared other diets. In addition, dietary polyphenols demonstrated clinically significant benefits metabolic microvascular functions leading lowering fasting cholesterol glucose, anti-inflammatory antioxidant properties high-risk T2DM patients. Conclusions: diets addition oil nuts reduced total body weight improved glucose metabolism.